Imaging Infection & Inflammation
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چکیده
Infectious diseases are common world wide, especially in developing countries. Some of these are relatively easy to diagnose at the bedside on the clinical picture alone (e.g. Measles, mumps, chicken pox). Some infections produce localising signs (e.g. Neck stiffness in meningitis, pain and tenderness over mastoids, sinuses, bone and joints, pleurisy, pneumonia, gall bladder and appendix), which can be further investigated by common imaging techniques (plain x-ray, ultrasound). Many common and important infections like typhoid, malaria and tuberculosis may not produce any localising signs hence diagnosis is difficult. The clinician is faced with 3 questions in a patient with fever.
منابع مشابه
Synthesis, formulation and quality control of 99mTc-HYNIC-hlgG for imaging focal sites of infection and inflammation in human subjects [Persian]
Imaging of infection and inflammation is an important issue in nuclear medicine as it may have relevant implication for the management of patients with infections or inflammatory diseases. In this regard the synthesis of human polyclonal immunoglobuline G (IgG) radiolabeled with technetium-99m (99mTc) by a novel method, via a nicotinamide hydrazine derivative, was performed. The biologica...
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Nuclear medicine imaging has been used to localize infection sites and efforts have been continued to develop modified infection specific radiopharmaceuticals. In this study gemifloxacin as a broad-spectrum quinolone has been labeled with [99mTc (CO)3 (H2O)3]+ core in order to evaluate its feasibility as an infection imaging agent for in vivo use. The stability of radioconjugate was checked in ...
متن کاملTechnetium-99m tricarbonyl labeled a broad-spectrum quinolone as a specific imaging agent in infection diseases
Nuclear medicine imaging has been used to localize infection sites and efforts have been continued to develop modified infection specific radiopharmaceuticals. In this study gemifloxacin as a broad-spectrum quinolone has been labeled with [99mTc (CO)3 (H2O)3]+ core in order to evaluate its feasibility as an infection imaging agent for in vivo use. The stability of radioconjugate was checked in ...
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Introduction: Differentiation between infection and sterile inflammation is one of the most difficult medical problems and is relevant in many clinical situations. Scintigraphy with radiolabeled antibiotics, еspecially labeled fluoroquinolones, is a promising tool for diagnosing bacterial inflammation. We have attempted to synthesize 99mTc-norfloxacin and studied its properties in ex...
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Ubiquicidin (UBI) [29-41] is a synthetic cationic antimicrobial peptide that preferentially binds to bacterial cell membrane at the site of infection. We aimed to assess diagnostic value of 99mTc-UBI [29-41] as a radiopharmaceutical in differentiation of bacterial infection from sterile inflammation in suspected orthopedic implants. Nine patients suspected for orthopedic implant infection, all ...
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